TK-EPN862 - Patient-dervied xenograft model of Posterior Fossa A Ependymoma - WGS

1 Dataset 1 Publication

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Dataset ID	Description	Technology	Samples
EGAD00001010008	In Vivo Loss of Tumorigenicity in a Patient-Derived Orthotopic Xenograft Mouse Model of Ependymoma. Whitehouse et al. 2023 Frontiers in Oncology. We describe the establishment of a patient-derived orthotopic xenograft (PDOX) model of posterior fossa A (PFA) EPN, derived from a metastatic cranial lesion. Patient and PDOX tumors were analyzed using RNA sequencing. WSG data (paired end) provided here correspond to germline DNA, Surgical sample 4 (described in the above manuscript as a cranial metastasis of PFA ependymoma), and a patient-derived xenograft derived from the patient.	HiSeq X Ten unspecified	10

Publications	Citations
<i>In vivo</i> loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma. Whitehouse JP, Hii H, Mayoh C, Wong M, Ajuyah P, Barahona P, Cui L, Dholaria H, White CL, Buntine MK, Byrne J, Rodrigues da Silva K, Howlett M, Girard EJ, Tsoli M, Ziegler DS, Dyke JM, Lee S, Ekert PG, Cowley MJ, Gottardo NG, Endersby R. Front Oncol 13: 2023 1123492	2