Paired healthy & tumor organoid Biobank _B16PON

B16PON consists of a panel of organoids (three-dimensional cell cultures) of premalignant epithelial cells of the colon and rectum. These organoids are derived from adenomas that are resected during a colonoscopy procedure. These can be propagated indefinitely and can be used to answer different research questions.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001008949	Organoid cultures derived from colorectal adenomas. RNA and DNA was isolated from these cultures for genome wide profiling.	Illumina HiSeq 2500	1

Publications	Citations
Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature. Martens-de Kemp SR, Komor MA, Hegi R, Bolijn AS, Tijssen M, de Groen FLM, Depla A, van Leerdam M, Meijer GA, Fijneman RJA, Carvalho B. Neoplasia 32: 2022 100820	4