Genetic landscape of pediatric ependymoma - EGA European Genome-Phenome Archive

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001000162	DATA FILES FOR SJEPD	Illumina HiSeq 2000	44
EGAD00001000853	DATA FILES FOR SJEPD	Illumina HiSeq 2000	37
EGAD00001000854	DATA FILES FOR SJEPD	Illumina HiSeq 2000	77
EGAD00001001432	PCGP Germline Study Whole Genome Sequencing	Illumina HiSeq 2000	1337
EGAD00001001433	PCGP Germline Study Whole Exome Sequencing	Illumina HiSeq 2000	906

Publications	Citations
Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. Parker M, Chen X, Bahrami A, Dalton J, Rusch M, Wu G, Easton J, Cheung NK, Dyer M, Mardis ER, Wilson RK, Mullighan C, Gilbertson R, Baker SJ, Zambetti G, Ellison DW, Downing JR, Zhang J, Pediatric Cancer Genome Project. Genome Biol 13: 2012 R113	22
C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma. Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y, Lee R, Tatevossian RG, Phoenix TN, Thiruvenkatam R, White E, Tang B, Orisme W, Gupta K, Rusch M, Chen X, Li Y, Nagahawhatte P, Hedlund E, Finkelstein D, Wu G, Shurtleff S, Easton J, Boggs K, Yergeau D, Vadodaria B, Mulder HL, Becksfort J, Gupta P, Huether R, Ma J, Song G, Gajjar A, Merchant T, Boop F, Smith AA, Ding L, Lu C, Ochoa K, Zhao D, Fulton RS, Fulton LL, Mardis ER, Wilson RK, Downing JR, Green DR, Zhang J, Ellison DW, Gilbertson RJ. Nature 506: 2014 451-455	360
CICERO: a versatile method for detecting complex and diverse driver fusions using cancer RNA sequencing data. Tian L, Li Y, Edmonson MN, Zhou X, Newman S, McLeod C, Thrasher A, Liu Y, Tang B, Rusch MC, Easton J, Ma J, Davis E, Trull A, Michael JR, Szlachta K, Mullighan C, Baker SJ, Downing JR, Ellison DW, Zhang J. Genome Biol 21: 2020 126	56
C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation. Ozawa T, Kaneko S, Szulzewsky F, Qiao Z, Takadera M, Narita Y, Kondo T, Holland EC, Hamamoto R, Ichimura K. Acta Neuropathol Commun 9: 2021 36	14
The landscape of coding RNA editing events in pediatric cancer. Wen J, Rusch M, Brady SW, Shao Y, Edmonson MN, Shaw TI, Powers BB, Tian L, Easton J, Mullighan CG, Gruber T, Ellison D, Zhang J. BMC Cancer 21: 2021 1233	6
Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers. Thatikonda V, Islam SMA, Autry RJ, Jones BC, Gröbner SN, Warsow G, Hutter B, Huebschmann D, Fröhling S, Kool M, Blattner-Johnson M, Jones DTW, Alexandrov LB, Pfister SM, Jäger N. Nat Cancer 4: 2023 276-289	13