A Large-Scale, Consortium-Based Genomewide Association Study of Asthma
We carried out a genomewide association study by genotyping 10,365 persons with physician-diagnosed asthma and 16,110 unaffected persons, all of whom were matched for ancestry. We used random-effects pooled analysis to test for association in the overall study population and in subgroups of subjects with childhood-onset asthma (defined as asthma developing before 16 years of age), later-onset asthma, severe asthma, and occupational asthma.
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00000000073 | 1 | ||
| EGAD00000000074 | 1 | ||
| EGAD00000000075 | 1 | ||
| EGAD00000000076 | 1 | ||
| EGAD00000000077 | 1 | ||
| EGAD00000000082 | 1 | ||
| EGAD00000000083 | 1 | ||
| EGAD00000000084 | 1 | ||
| EGAD00000000085 | 1 | ||
| EGAD00000000086 | 1 | ||
| EGAD00000000087 | 1 | ||
| EGAD00000000088 | 1 | ||
| EGAD00000000089 | 1 | ||
| EGAD00000000090 | 1 | ||
| EGAD00000000091 | 1 | ||
| EGAD00000000092 | 1 | ||
| EGAD00000000093 | 1 | ||
| EGAD00000000094 | 1 | ||
| EGAD00000000101 | 1 | ||
| EGAD00000000102 | 1 | ||
| EGAD00000000103 | 1 | ||
| EGAD00000000104 | 1 | ||
| EGAD00000000105 | 1 | ||
| EGAD00000000106 | 1 | ||
| EGAD00000000107 | 1 | ||
| EGAD00000000108 | 1 | ||
| EGAD00000000109 | 1 |
| Publications | Citations |
|---|---|
|
A large-scale, consortium-based genomewide association study of asthma.
N Engl J Med 363: 2010 1211-1221 |
1184 |
|
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
J Allergy Clin Immunol 130: 2012 861-8.e7 |
89 |
|
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.
J Allergy Clin Immunol 132: 2013 313-20.e15 |
69 |
|
Expression of asthma susceptibility genes in bronchial epithelial cells and bronchial alveolar lavage in the Severe Asthma Research Program (SARP) cohort.
J Asthma 53: 2016 775-782 |
16 |
|
Genome-wide search identifies a gene-gene interaction between 20p13 and 2q14 in asthma.
BMC Genet 17: 2016 102 |
2 |
|
Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.
PLoS Med 14: 2017 e1002294 |
44 |