Genome-wide association scan in Parkinson's disease - EGA European Genome-Phenome Archive

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00000000021	WTCCC2 project samples from 1958 British Birth Cohort		3000
EGAD00000000022	WTCCC2 project samples from 1958 British Birth Cohort		3000
EGAD00000000023	WTCCC2 project samples from National Blood Donors (NBS) Cohort		1
EGAD00000000024	WTCCC2 project samples from National Blood Donors (NBS) Cohort		1
EGAD00000000057	WTCCC project samples from the Parkinson's disase cohort	Illumina 610K Quad	1705

Publications	Citations
Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. UK Parkinson's Disease Consortium, Wellcome Trust Case Control Consortium 2, Spencer CC, Plagnol V, Strange A, Gardner M, Paisan-Ruiz C, Band G, Barker RA, Bellenguez C, Bhatia K, Blackburn H, Blackwell JM, Bramon E, Brown MA, Brown MA, Burn D, Casas JP, Chinnery PF, Clarke CE, Corvin A, Craddock N, Deloukas P, Edkins S, Evans J, Freeman C, Gray E, Hardy J, Hudson G, Hunt S, Jankowski J, Langford C, Lees AJ, Markus HS, Mathew CG, McCarthy MI, Morrison KE, Palmer CN, Pearson JP, Peltonen L, Pirinen M, Plomin R, Potter S, Rautanen A, Sawcer SJ, Su Z, Trembath RC, Viswanathan AC, Williams NW, Morris HR, Donnelly P, Wood NW. Hum Mol Genet 20: 2011 345-353	141
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression. Soldner F, Stelzer Y, Shivalila CS, Abraham BJ, Latourelle JC, Barrasa MI, Goldmann J, Myers RH, Young RA, Jaenisch R. Nature 533: 2016 95-99	314
Imputation of DNA Methylation Levels in the Brain Implicates a Risk Factor for Parkinson's Disease. Rawlik K, Rowlatt A, Tenesa A. Genetics 204: 2016 771-781	11
SumHer better estimates the SNP heritability of complex traits from summary statistics. Speed D, Balding DJ. Nat Genet 51: 2019 277-284	100
Midnolin is a confirmed genetic risk factor for Parkinson's disease. Obara Y, Sato H, Nakayama T, Kato T, Ishii K. Ann Clin Transl Neurol 6: 2019 2205-2211	6
Common X-Chromosome Variants Are Associated with Parkinson Disease Risk. Le Guen Y, Napolioni V, Belloy ME, Yu E, Krohn L, Ruskey JA, Gan-Or Z, Kennedy G, Eger SJ, Greicius MD. Ann Neurol 90: 2021 22-34	20
Automated machine learning for genome wide association studies. Lakiotaki K, Papadovasilakis Z, Lagani V, Fafalios S, Charonyktakis P, Tsagris M, Tsamardinos I. Bioinformatics 39: 2023 btad545	1