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ICR639 CPG NGS Validation series

The dataset includes sequencing data generated using the TruSight Cancer Panel (TSCP) a targeted NGS assay for analysis of CPGs and orthogonally generated data supporting at least one pathogenic variant in a CPG for a total of 645 pathogenic CPG variants. The set of pathogenic CPG variants includes strong representation of some of the most challenging types of pathogenic variants, with 339 indels, including 16 complex indels and 24 insertions or deletions with length greater than 5bp, and 74 exon CNVs, including 23 single exon CNVs. There are 502 pathogenic variants in BRCA1 or BRCA2, making this an important first-line validation dataset for laboratories performing NGS testing of BRCA1 and BRCA2.

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Accessing ICR-GSR data archived in EGA

ICR - Genetic Susceptibility Research (ICR-GSR)Data Access CommitteeAccession number: EGAC00001000235Details of the ICR-GSR Data Access Committee are available for each of the datasets accessible via www.icr.ac.uk/genetic-resourcesAlternatively, please email rahmanlab@icr.ac.uk, giving the above Accession number in the subject line, to request an Application Form for access. This should be completed and and returned to rahmanlab@icr.ac.uk. Applications will only be accepted electronically. Any queries regarding access procedures or completion of the forms should be sent to this email address. Once access has been approved, an agreement will need to be completed. A signed hard copy of the agreement should e-mailed, faxed or posted to: Professor Nazneen Rahman The Institute of Cancer Research, London Division of Genetics & Epidemiology 15 Cotswold Road Sutton SM2 5NG UNITED KINGDOMEmail: rahmanlab@icr.ac.uk Fax: =44(0)20 8722 4359

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001002993 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002013941 fastq.gz 313.9 MB
EGAF00002013942 fastq.gz 321.9 MB
EGAF00002013943 fastq.gz 320.0 MB
EGAF00002013944 fastq.gz 356.7 MB
EGAF00002013945 fastq.gz 260.5 MB
EGAF00002013946 fastq.gz 285.2 MB
EGAF00002013947 fastq.gz 378.0 MB
EGAF00002013948 fastq.gz 386.5 MB
EGAF00002013949 fastq.gz 516.1 MB
EGAF00002013950 fastq.gz 505.9 MB
EGAF00002013951 fastq.gz 183.4 MB
EGAF00002013952 fastq.gz 188.6 MB
EGAF00002013953 fastq.gz 396.4 MB
EGAF00002013954 fastq.gz 409.6 MB
EGAF00002013955 fastq.gz 335.8 MB
EGAF00002013956 fastq.gz 345.3 MB
EGAF00002013957 fastq.gz 257.6 MB
EGAF00002013958 fastq.gz 263.9 MB
EGAF00002013959 fastq.gz 279.9 MB
EGAF00002013960 fastq.gz 296.7 MB
EGAF00002013961 fastq.gz 366.5 MB
EGAF00002013962 fastq.gz 382.6 MB
EGAF00002013963 fastq.gz 264.3 MB
EGAF00002013964 fastq.gz 276.4 MB
EGAF00002013965 fastq.gz 272.4 MB
EGAF00002013966 fastq.gz 280.3 MB
EGAF00002013967 fastq.gz 335.4 MB
EGAF00002013968 fastq.gz 344.4 MB
EGAF00002013969 fastq.gz 320.9 MB
EGAF00002013970 fastq.gz 351.5 MB
EGAF00002013971 fastq.gz 472.5 MB
EGAF00002013972 fastq.gz 462.9 MB
EGAF00002013973 fastq.gz 267.5 MB
EGAF00002013974 fastq.gz 267.7 MB
EGAF00002013975 fastq.gz 318.5 MB
EGAF00002013976 fastq.gz 316.4 MB
EGAF00002013977 fastq.gz 282.3 MB
EGAF00002013978 fastq.gz 289.9 MB
EGAF00002013979 fastq.gz 352.8 MB
EGAF00002013980 fastq.gz 356.7 MB
EGAF00002013981 fastq.gz 350.8 MB
EGAF00002013982 fastq.gz 386.3 MB
EGAF00002013983 fastq.gz 317.5 MB
EGAF00002013984 fastq.gz 323.2 MB
EGAF00002013985 fastq.gz 266.4 MB
EGAF00002013986 fastq.gz 272.5 MB
EGAF00002013987 fastq.gz 338.3 MB
EGAF00002013988 fastq.gz 350.0 MB
EGAF00002013989 fastq.gz 314.5 MB
EGAF00002013990 fastq.gz 320.6 MB
EGAF00002013991 fastq.gz 326.9 MB
EGAF00002013992 fastq.gz 345.3 MB
EGAF00002013993 fastq.gz 209.9 MB
EGAF00002013994 fastq.gz 212.8 MB
EGAF00002013995 fastq.gz 304.2 MB
EGAF00002013996 fastq.gz 310.3 MB
EGAF00002013997 fastq.gz 279.6 MB
EGAF00002013998 fastq.gz 299.7 MB
EGAF00002013999 fastq.gz 130.4 MB
EGAF00002014000 fastq.gz 132.2 MB
EGAF00002014001 fastq.gz 524.5 MB
EGAF00002014002 fastq.gz 537.3 MB
EGAF00002014003 fastq.gz 253.1 MB
EGAF00002014004 fastq.gz 257.5 MB
EGAF00002014005 fastq.gz 387.0 MB
EGAF00002014006 fastq.gz 432.9 MB
EGAF00002014007 fastq.gz 332.1 MB
EGAF00002014008 fastq.gz 364.3 MB
EGAF00002014009 fastq.gz 401.6 MB
EGAF00002014010 fastq.gz 441.7 MB
EGAF00002014011 fastq.gz 319.3 MB
EGAF00002014012 fastq.gz 333.2 MB
EGAF00002014013 fastq.gz 539.7 MB
EGAF00002014014 fastq.gz 594.3 MB
EGAF00002014015 fastq.gz 386.1 MB
EGAF00002014016 fastq.gz 424.2 MB
EGAF00002014017 fastq.gz 325.2 MB
EGAF00002014018 fastq.gz 360.8 MB
EGAF00002014019 fastq.gz 314.6 MB
EGAF00002014020 fastq.gz 343.6 MB
EGAF00002014021 fastq.gz 346.1 MB
EGAF00002014022 fastq.gz 379.7 MB
EGAF00002014023 fastq.gz 471.7 MB
EGAF00002014024 fastq.gz 521.3 MB
EGAF00002014025 fastq.gz 269.6 MB
EGAF00002014026 fastq.gz 272.9 MB
EGAF00002014027 fastq.gz 358.7 MB
EGAF00002014028 fastq.gz 370.0 MB
EGAF00002014029 fastq.gz 244.6 MB
EGAF00002014030 fastq.gz 241.3 MB
EGAF00002014031 fastq.gz 263.7 MB
EGAF00002014032 fastq.gz 273.5 MB
EGAF00002014033 fastq.gz 375.6 MB
EGAF00002014034 fastq.gz 375.4 MB
EGAF00002014035 fastq.gz 306.2 MB
EGAF00002014036 fastq.gz 315.2 MB
EGAF00002014037 fastq.gz 235.3 MB
EGAF00002014038 fastq.gz 244.4 MB
EGAF00002014039 fastq.gz 376.6 MB
EGAF00002014040 fastq.gz 384.5 MB
EGAF00002014041 fastq.gz 310.6 MB
EGAF00002014042 fastq.gz 320.0 MB
EGAF00002014043 fastq.gz 169.2 MB
EGAF00002014044 fastq.gz 173.0 MB
EGAF00002014045 fastq.gz 311.0 MB
EGAF00002014046 fastq.gz 330.0 MB
EGAF00002014047 fastq.gz 216.8 MB
EGAF00002014048 fastq.gz 219.9 MB
EGAF00002014049 fastq.gz 227.0 MB
EGAF00002014050 fastq.gz 244.4 MB
EGAF00002014051 fastq.gz 233.3 MB
EGAF00002014052 fastq.gz 247.3 MB
EGAF00002014053 fastq.gz 341.4 MB
EGAF00002014054 fastq.gz 350.6 MB
EGAF00002014055 fastq.gz 427.5 MB
EGAF00002014056 fastq.gz 458.6 MB
EGAF00002014057 fastq.gz 323.4 MB
EGAF00002014058 fastq.gz 331.5 MB
EGAF00002014059 fastq.gz 341.3 MB
EGAF00002014060 fastq.gz 350.1 MB
EGAF00002014061 fastq.gz 481.3 MB
EGAF00002014062 fastq.gz 485.4 MB
EGAF00002014063 fastq.gz 320.0 MB
EGAF00002014064 fastq.gz 321.3 MB
EGAF00002014065 fastq.gz 372.7 MB
EGAF00002014066 fastq.gz 377.7 MB
EGAF00002014067 fastq.gz 341.8 MB
EGAF00002014068 fastq.gz 351.0 MB
EGAF00002014069 fastq.gz 761.5 MB
EGAF00002014070 fastq.gz 784.4 MB
EGAF00002014071 fastq.gz 295.4 MB
EGAF00002014072 fastq.gz 305.7 MB
EGAF00002014073 fastq.gz 343.1 MB
EGAF00002014074 fastq.gz 347.8 MB
EGAF00002014075 fastq.gz 458.4 MB
EGAF00002014076 fastq.gz 469.7 MB
EGAF00002014077 fastq.gz 302.3 MB
EGAF00002014078 fastq.gz 308.8 MB
EGAF00002014079 fastq.gz 295.5 MB
EGAF00002014080 fastq.gz 308.7 MB
EGAF00002014081 fastq.gz 324.4 MB
EGAF00002014082 fastq.gz 358.5 MB
EGAF00002014083 fastq.gz 409.2 MB
EGAF00002014084 fastq.gz 450.3 MB
EGAF00002014085 fastq.gz 413.8 MB
EGAF00002014086 fastq.gz 417.6 MB
EGAF00002014087 fastq.gz 240.6 MB
EGAF00002014088 fastq.gz 242.6 MB
EGAF00002014089 fastq.gz 322.6 MB
EGAF00002014090 fastq.gz 370.5 MB
EGAF00002014091 fastq.gz 358.0 MB
EGAF00002014092 fastq.gz 392.5 MB
EGAF00002014093 fastq.gz 286.1 MB
EGAF00002014094 fastq.gz 318.8 MB
EGAF00002014095 fastq.gz 411.8 MB
EGAF00002014096 fastq.gz 454.7 MB
EGAF00002014097 fastq.gz 367.8 MB
EGAF00002014098 fastq.gz 404.2 MB
EGAF00002014099 fastq.gz 337.4 MB
EGAF00002014100 fastq.gz 368.6 MB
EGAF00002014101 fastq.gz 365.7 MB
EGAF00002014102 fastq.gz 374.1 MB
EGAF00002014103 fastq.gz 306.0 MB
EGAF00002014104 fastq.gz 316.1 MB
EGAF00002014105 fastq.gz 273.2 MB
EGAF00002014106 fastq.gz 277.2 MB
EGAF00002014107 fastq.gz 317.9 MB
EGAF00002014108 fastq.gz 323.1 MB
EGAF00002014109 fastq.gz 494.2 MB
EGAF00002014110 fastq.gz 502.0 MB
EGAF00002014111 fastq.gz 288.2 MB
EGAF00002014112 fastq.gz 298.0 MB
EGAF00002014113 fastq.gz 373.4 MB
EGAF00002014114 fastq.gz 383.8 MB
EGAF00002014115 fastq.gz 266.4 MB
EGAF00002014116 fastq.gz 292.2 MB
EGAF00002014117 fastq.gz 311.2 MB
EGAF00002014118 fastq.gz 341.0 MB
EGAF00002014119 fastq.gz 270.1 MB
EGAF00002014120 fastq.gz 296.8 MB
EGAF00002014121 fastq.gz 348.4 MB
EGAF00002014122 fastq.gz 381.9 MB
EGAF00002014123 fastq.gz 327.2 MB
EGAF00002014124 fastq.gz 355.5 MB
EGAF00002014125 fastq.gz 369.0 MB
EGAF00002014126 fastq.gz 404.5 MB
EGAF00002014127 fastq.gz 287.5 MB
EGAF00002014128 fastq.gz 313.1 MB
EGAF00002014129 fastq.gz 261.8 MB
EGAF00002014130 fastq.gz 289.5 MB
EGAF00002014131 fastq.gz 290.9 MB
EGAF00002014132 fastq.gz 318.8 MB
EGAF00002014133 fastq.gz 498.3 MB
EGAF00002014134 fastq.gz 481.6 MB
EGAF00002014135 fastq.gz 235.4 MB
EGAF00002014136 fastq.gz 240.8 MB
EGAF00002014137 fastq.gz 367.3 MB
EGAF00002014138 fastq.gz 404.2 MB
EGAF00002014139 fastq.gz 362.6 MB
EGAF00002014140 fastq.gz 370.8 MB
EGAF00002014141 fastq.gz 372.3 MB
EGAF00002014142 fastq.gz 378.3 MB
EGAF00002014143 fastq.gz 404.4 MB
EGAF00002014144 fastq.gz 414.0 MB
EGAF00002014145 fastq.gz 360.0 MB
EGAF00002014146 fastq.gz 365.6 MB
EGAF00002014147 fastq.gz 349.1 MB
EGAF00002014148 fastq.gz 348.5 MB
EGAF00002014149 fastq.gz 326.1 MB
EGAF00002014150 fastq.gz 341.6 MB
EGAF00002014151 fastq.gz 290.3 MB
EGAF00002014152 fastq.gz 293.7 MB
EGAF00002014153 fastq.gz 316.8 MB
EGAF00002014154 fastq.gz 327.2 MB
EGAF00002014155 fastq.gz 270.5 MB
EGAF00002014156 fastq.gz 279.7 MB
EGAF00002014157 fastq.gz 265.0 MB
EGAF00002014158 fastq.gz 267.0 MB
EGAF00002014159 fastq.gz 307.9 MB
EGAF00002014160 fastq.gz 313.5 MB
EGAF00002014161 fastq.gz 329.9 MB
EGAF00002014162 fastq.gz 337.0 MB
EGAF00002014163 fastq.gz 236.3 MB
EGAF00002014164 fastq.gz 238.9 MB
EGAF00002014165 fastq.gz 373.2 MB
EGAF00002014166 fastq.gz 384.0 MB
EGAF00002014167 fastq.gz 376.5 MB
EGAF00002014168 fastq.gz 387.0 MB
EGAF00002014169 fastq.gz 247.3 MB
EGAF00002014170 fastq.gz 257.9 MB
EGAF00002014171 fastq.gz 273.6 MB
EGAF00002014172 fastq.gz 279.0 MB
EGAF00002014173 fastq.gz 260.4 MB
EGAF00002014174 fastq.gz 262.2 MB
EGAF00002014175 fastq.gz 275.9 MB
EGAF00002014176 fastq.gz 283.4 MB
EGAF00002014177 fastq.gz 311.9 MB
EGAF00002014178 fastq.gz 325.9 MB
EGAF00002014179 fastq.gz 304.8 MB
EGAF00002014180 fastq.gz 310.4 MB
EGAF00002014181 fastq.gz 378.2 MB
EGAF00002014182 fastq.gz 384.5 MB
EGAF00002014183 fastq.gz 261.4 MB
EGAF00002014184 fastq.gz 267.8 MB
EGAF00002014185 fastq.gz 343.0 MB
EGAF00002014186 fastq.gz 363.5 MB
EGAF00002014187 fastq.gz 281.1 MB
EGAF00002014188 fastq.gz 292.4 MB
EGAF00002014189 fastq.gz 201.8 MB
EGAF00002014190 fastq.gz 205.9 MB
EGAF00002014191 fastq.gz 285.3 MB
EGAF00002014192 fastq.gz 288.6 MB
EGAF00002014193 fastq.gz 267.0 MB
EGAF00002014194 fastq.gz 274.3 MB
EGAF00002014195 fastq.gz 299.7 MB
EGAF00002014196 fastq.gz 308.8 MB
EGAF00002014197 fastq.gz 315.5 MB
EGAF00002014198 fastq.gz 324.2 MB
EGAF00002014199 fastq.gz 278.5 MB
EGAF00002014200 fastq.gz 287.8 MB
EGAF00002014201 fastq.gz 305.4 MB
EGAF00002014202 fastq.gz 309.6 MB
EGAF00002014203 fastq.gz 255.4 MB
EGAF00002014204 fastq.gz 258.5 MB
EGAF00002014205 fastq.gz 345.6 MB
EGAF00002014206 fastq.gz 350.7 MB
EGAF00002014207 fastq.gz 641.4 MB
EGAF00002014208 fastq.gz 666.8 MB
EGAF00002014209 fastq.gz 277.3 MB
EGAF00002014210 fastq.gz 297.7 MB
EGAF00002014211 fastq.gz 265.1 MB
EGAF00002014212 fastq.gz 269.9 MB
EGAF00002014213 fastq.gz 439.2 MB
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EGAF00002014215 fastq.gz 324.8 MB
EGAF00002014216 fastq.gz 314.9 MB
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EGAF00002014218 fastq.gz 555.8 MB
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EGAF00002014222 fastq.gz 225.4 MB
EGAF00002014223 fastq.gz 214.1 MB
EGAF00002014224 fastq.gz 228.0 MB
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EGAF00002014236 fastq.gz 351.9 MB
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EGAF00002014256 fastq.gz 406.0 MB
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1917 Files (423.7 GB)