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Use of Deep Sequencing to Dectect Clonal Mutations In Sun Exposed Skin Epidermis

This study aims to define the landscape of somatic mutations in sun exposed human skin by deep sequencing, analyse their frequency and use the data to infer the effect of mutations on proliferating cell behaviour. The frequency of each mutation will reflect the size of the clone of cells in the tissue sample. By analyzing small samples, clones with as few as 100 cells will be detectable. Allele frequency distributions for each mutation will be used to infer cell fate using published methods (Klein et al. 2010). This study will shed unprecedented light on the early clonal events that lead to the emergence of cancer.

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Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001000515 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00000602465 bam 904.1 MB
EGAF00000602466 bam 1.2 GB
EGAF00000602467 bam 986.0 MB
EGAF00000602468 bam 1.1 GB
EGAF00000602469 bam 1.0 GB
EGAF00000602470 bam 976.0 MB
EGAF00000602471 bam 957.9 MB
EGAF00000602472 bam 927.0 MB
EGAF00000602473 bam 1.0 GB
EGAF00000602474 bam 1.3 GB
EGAF00000602475 bam 1.2 GB
EGAF00000602476 bam 1.0 GB
EGAF00000602477 bam 1.1 GB
EGAF00000602478 bam 1.2 GB
EGAF00000602479 bam 935.3 MB
EGAF00000602480 bam 1.2 GB
EGAF00000602481 bam 831.5 MB
EGAF00000602482 bam 877.9 MB
EGAF00000602483 bam 1.1 GB
EGAF00000602484 bam 1.4 GB
EGAF00000602485 bam 893.2 MB
EGAF00000602486 bam 1.2 GB
EGAF00000602487 bam 1.1 GB
EGAF00000602488 bam 1.0 GB
EGAF00000602489 bam 1.0 GB
EGAF00000602490 bam 971.1 MB
EGAF00000602491 bam 1.1 GB
EGAF00000602492 bam 994.2 MB
EGAF00000602493 bam 1.0 GB
EGAF00000602494 bam 810.3 MB
EGAF00000602495 bam 991.2 MB
EGAF00000602496 bam 1.9 GB
EGAF00000602497 cram 430.7 MB
EGAF00000602498 cram 571.3 MB
EGAF00000602499 cram 475.4 MB
EGAF00000602500 cram 518.9 MB
EGAF00000602501 cram 495.2 MB
EGAF00000602502 cram 468.9 MB
EGAF00000602503 cram 462.2 MB
EGAF00000602504 cram 449.5 MB
EGAF00000602505 cram 488.4 MB
EGAF00000602506 cram 629.0 MB
EGAF00000602507 cram 578.5 MB
EGAF00000602508 cram 494.5 MB
EGAF00000602509 cram 512.0 MB
EGAF00000602510 cram 583.5 MB
EGAF00000602511 cram 451.9 MB
EGAF00000602512 cram 595.7 MB
EGAF00000602513 cram 395.5 MB
EGAF00000602514 cram 446.1 MB
EGAF00000602515 cram 534.4 MB
EGAF00000602516 cram 662.2 MB
EGAF00000602517 cram 429.1 MB
EGAF00000602518 cram 555.1 MB
EGAF00000602519 cram 518.7 MB
EGAF00000602520 cram 490.0 MB
EGAF00000602521 cram 505.1 MB
EGAF00000602522 cram 476.3 MB
EGAF00000602523 cram 547.4 MB
EGAF00000602524 cram 489.1 MB
EGAF00000602525 cram 492.8 MB
EGAF00000602526 cram 394.1 MB
EGAF00000602527 cram 486.5 MB
EGAF00000602528 cram 978.3 MB
EGAF00000602529 cram 430.9 MB
EGAF00000602530 cram 570.7 MB
EGAF00000602531 cram 474.7 MB
EGAF00000602532 cram 517.7 MB
EGAF00000602533 cram 494.8 MB
EGAF00000602534 cram 468.5 MB
EGAF00000602535 cram 461.4 MB
EGAF00000602536 cram 448.5 MB
EGAF00000602537 cram 488.1 MB
EGAF00000602538 cram 627.4 MB
EGAF00000602539 cram 577.8 MB
EGAF00000602540 cram 494.2 MB
EGAF00000602541 cram 511.1 MB
EGAF00000602542 cram 582.6 MB
EGAF00000602543 cram 452.0 MB
EGAF00000602544 cram 594.7 MB
EGAF00000602545 cram 394.8 MB
EGAF00000602546 cram 443.9 MB
EGAF00000602547 cram 533.5 MB
EGAF00000602548 cram 660.7 MB
EGAF00000602549 cram 428.9 MB
EGAF00000602550 cram 553.9 MB
EGAF00000602551 cram 518.5 MB
EGAF00000602552 cram 488.7 MB
EGAF00000602553 cram 504.2 MB
EGAF00000602554 cram 475.7 MB
EGAF00000602555 cram 545.5 MB
EGAF00000602556 cram 488.2 MB
EGAF00000602557 cram 492.4 MB
EGAF00000602558 cram 393.8 MB
EGAF00000602559 cram 485.8 MB
EGAF00000602560 cram 976.1 MB
EGAF00000602561 cram 431.6 MB
EGAF00000602562 cram 571.2 MB
EGAF00000602563 cram 475.8 MB
EGAF00000602564 cram 518.8 MB
EGAF00000602565 cram 495.3 MB
EGAF00000602566 cram 469.1 MB
EGAF00000602567 cram 462.3 MB
EGAF00000602568 cram 449.5 MB
EGAF00000602569 cram 488.5 MB
EGAF00000602570 cram 628.6 MB
EGAF00000602571 cram 578.9 MB
EGAF00000602572 cram 494.5 MB
EGAF00000602573 cram 511.8 MB
EGAF00000602574 cram 583.5 MB
EGAF00000602575 cram 452.2 MB
EGAF00000602576 cram 595.8 MB
EGAF00000602577 cram 396.1 MB
EGAF00000602578 cram 445.3 MB
EGAF00000602579 cram 534.1 MB
EGAF00000602580 cram 662.1 MB
EGAF00000602581 cram 429.7 MB
EGAF00000602582 cram 554.5 MB
EGAF00000602583 cram 518.8 MB
EGAF00000602584 cram 490.3 MB
EGAF00000602585 cram 503.8 MB
EGAF00000602586 cram 476.1 MB
EGAF00000602587 cram 546.5 MB
EGAF00000602588 cram 489.0 MB
EGAF00000602589 cram 492.6 MB
EGAF00000602590 cram 394.2 MB
EGAF00000602591 cram 486.1 MB
EGAF00000602592 cram 976.6 MB
EGAF00000606417 cram 2.5 GB
EGAF00000606418 cram 2.4 GB
EGAF00000606419 cram 2.3 GB
EGAF00000606420 cram 2.2 GB
EGAF00000606421 cram 2.4 GB
EGAF00000606422 cram 2.4 GB
EGAF00000606423 cram 2.4 GB
EGAF00000614806 cram 711.3 MB
EGAF00000614807 cram 660.1 MB
EGAF00000614808 cram 531.3 MB
EGAF00000614809 cram 434.8 MB
EGAF00000614810 cram 1.4 GB
EGAF00000614811 cram 493.5 MB
EGAF00000614812 cram 596.5 MB
EGAF00000614813 cram 651.3 MB
EGAF00000614814 cram 622.8 MB
EGAF00000614815 cram 702.7 MB
EGAF00000614816 cram 457.0 MB
EGAF00000614817 cram 991.8 MB
EGAF00000614818 cram 670.9 MB
EGAF00000614819 cram 678.9 MB
EGAF00000614820 cram 521.9 MB
EGAF00000614821 cram 592.8 MB
EGAF00000614822 cram 913.7 MB
EGAF00000614823 cram 1.1 GB
EGAF00000614824 cram 949.1 MB
EGAF00000614825 cram 646.8 MB
EGAF00000614826 cram 957.4 MB
EGAF00000614827 cram 1.4 GB
EGAF00000614828 cram 969.7 MB
EGAF00000614829 cram 1.1 GB
EGAF00000614830 cram 1.3 GB
EGAF00000614831 cram 1.0 GB
EGAF00000614832 cram 1.2 GB
EGAF00000614833 cram 1.2 GB
EGAF00000614834 cram 554.6 MB
EGAF00000614835 cram 1.2 GB
EGAF00000614836 cram 1.2 GB
EGAF00000614837 cram 1.1 GB
EGAF00000614838 cram 931.3 MB
EGAF00000614839 cram 906.6 MB
EGAF00000614840 cram 1.1 GB
EGAF00000614841 cram 1.0 GB
EGAF00000614842 cram 1.1 GB
EGAF00000614843 cram 1.0 GB
EGAF00000614844 cram 996.9 MB
EGAF00000614845 cram 876.7 MB
EGAF00000614846 cram 949.4 MB
EGAF00000614847 cram 1.1 GB
EGAF00000614848 cram 942.9 MB
EGAF00000614849 cram 963.7 MB
EGAF00000614850 cram 1.1 GB
EGAF00000614851 cram 974.0 MB
EGAF00000614852 cram 243.7 MB
EGAF00000614853 cram 886.0 MB
EGAF00000614854 cram 1.0 GB
EGAF00000614855 cram 939.2 MB
EGAF00000614856 cram 942.5 MB
EGAF00000614857 cram 956.6 MB
EGAF00000614858 cram 969.3 MB
EGAF00000614859 cram 1.1 GB
EGAF00000614860 cram 1.0 GB
EGAF00000614861 cram 1.0 GB
EGAF00000614862 cram 941.0 MB
EGAF00000614863 cram 1.0 GB
EGAF00000614864 cram 969.6 MB
EGAF00000614865 cram 903.5 MB
EGAF00000614866 cram 883.8 MB
EGAF00000614867 cram 946.3 MB
EGAF00000614868 cram 977.7 MB
EGAF00000614869 cram 1.0 GB
EGAF00000614870 cram 905.6 MB
EGAF00000614871 cram 904.1 MB
EGAF00000614872 cram 919.7 MB
EGAF00000614873 cram 935.8 MB
EGAF00000614874 cram 574.8 MB
EGAF00000614875 cram 1.0 GB
EGAF00000614876 cram 1.0 GB
EGAF00000614877 cram 1.0 GB
EGAF00000614878 cram 886.2 MB
EGAF00000614879 cram 890.1 MB
EGAF00000614880 cram 883.7 MB
EGAF00000614881 cram 956.1 MB
EGAF00000614882 cram 1.0 GB
EGAF00000614883 cram 973.0 MB
EGAF00000614884 cram 1.0 GB
EGAF00000614885 cram 1.1 GB
EGAF00000614886 cram 657.9 MB
EGAF00000614887 cram 814.4 MB
EGAF00000614888 cram 847.2 MB
EGAF00000614889 cram 805.8 MB
EGAF00000614890 cram 841.8 MB
EGAF00000614891 cram 854.4 MB
EGAF00000614892 cram 894.3 MB
EGAF00000614893 cram 932.0 MB
EGAF00000614894 cram 807.3 MB
EGAF00000614895 cram 846.4 MB
EGAF00000614896 cram 888.3 MB
EGAF00000614897 cram 1.0 GB
EGAF00000614898 cram 954.9 MB
EGAF00000614899 cram 664.4 MB
EGAF00000614900 cram 866.9 MB
EGAF00000614901 cram 884.2 MB
EGAF00000684347 cram 886.5 MB
EGAF00000684348 cram 928.2 MB
EGAF00000684349 cram 948.2 MB
EGAF00000684350 cram 996.1 MB
EGAF00000684351 cram 1.3 GB
EGAF00000684352 cram 1.1 GB
EGAF00000684453 cram 1.2 GB
EGAF00000684454 cram 997.9 MB
EGAF00000684455 cram 902.6 MB
EGAF00000684456 cram 975.2 MB
EGAF00000684457 cram 948.5 MB
EGAF00000684458 cram 1.0 GB
EGAF00000684459 cram 977.3 MB
EGAF00000684460 cram 1.0 GB
EGAF00000684461 cram 1.1 GB
EGAF00000684462 cram 1.0 GB
EGAF00000684463 cram 1.0 GB
EGAF00000684464 cram 1.1 GB
EGAF00000684465 cram 1.3 GB
EGAF00000684466 cram 957.5 MB
EGAF00000684467 cram 1.0 GB
EGAF00000684468 cram 1.0 GB
EGAF00000684469 cram 1.1 GB
EGAF00000684470 cram 1.2 GB
EGAF00000684471 cram 1.0 GB
EGAF00000684472 cram 929.9 MB
EGAF00000684473 cram 977.6 MB
EGAF00000684474 cram 999.3 MB
EGAF00000684475 cram 1.9 GB
EGAF00000684476 cram 1.3 GB
EGAF00000684477 cram 1.2 GB
262 Files (220.7 GB)